Dr. Paulo Roberto Hrihorowitsch  Moreno
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Dr. Paulo Roberto Hrihorowitsch Moreno

Professor
Universidade de Sao Paulo, Brazil


Highest Degree
Ph.D. in Plant Biotechnology from Leiden University, The Netherlands

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Biography

Bachelor's at FarmÌcia from Universidade Federal do Rio Grande do Sul (1986), master's at Pharmacy from Universidade Federal do Rio Grande do Sul (1989) and doctorate at Plant Cell Biotechnology from Leiden University (1994). Has experience in Pharmacy, focusing on Pharmacognosy, acting on the following subjects: essential oils, alkaloids, antimicrobial activity, cosmetic applications

Area of Interest:

Biomedical Sciences
100%
Bioactive Components
62%
Natural Bioactive Compounds
90%
Phytotheraphy
75%
Antioxidant Agents
55%

Research Publications in Numbers

Books
0
Chapters
2
Articles
145
Abstracts
0

Selected Publications

  1. Silva, F.L., P.R.H. Moreno, A.C.H.F. Sawaya, G.C. de Freitas Lemeszenki, P. Hewitson and S. Ignatova, 2022. Dereplication of phenolics from Cardiospermum corindum by countercurrent chromatography combined with liquid chromatography-electrospray mass spectrometry. Rev. Bras. Farmacogn., 32: 280-285.
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  2. Reis-Silva, C.S.M., P.C. Branco, K. Lima, F.L. Silva and P.R.H. Moreno et al., 2021. Embelin potentiates venetoclax-induced apoptosis in acute myeloid leukemia cells. Toxicol. In Vitro, Vol. 76. 10.1016/j.tiv.2021.105207.
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  3. Grombone-Guaratini, M.T., C.M. Furlan, P.S. Lopes, K.P. Barsalobra, V.R. Leite e Silva and P.R.H. Moreno, 2021. Antioxidant and Photoprotective Properties of Neotropical Bamboo Species. In: Plant Antioxidants and Health, Ekiert, H.M., K.G. Ramawat and J. Arora (Eds.), Springer International Publishing, Cham, Switzerland, ISBN 978-3-030-45299-5, pp: 1-35.
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  4. Silva, F.L., A.E. Santo, P.C. Branco, L.V. Costa-Lotufo and M.C.M. Young et al., 2020. Antioxidant and cytotoxic properties of essential oils from native brazilian lauraceae species. Global J. Med. Res., 10.34257/GJMRBVOL19IS3PG1.
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  5. Silva, F.L., R.V.S. Silva, P.C. Branco, L.V. Costa-Lotufo and C. Murakami et al., 2020. Chemical composition of the Brazilian native Cinnamomum stenophyllum (Meisn.) Vattimo-Gil essential oil by GC-qMS and GC  GC-TOFMS, and its cytotoxic activity. Arabian J. Chem., 13: 4926-4935.
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  6. Wroblewska, K.B., D.C.S. de Oliveira, M.T. Grombone-Guaratini and P.R.H. Moreno, 2019. Medicinal Properties of Bamboos. In: Pharmacognosy: Medicinal Plants, Perveen, S. (Ed.). IntechOpen, London, UK., ISBN: 978-1-83880-611-8, pp: 1-18.
  7. Wroblewska, K.B., A.R. Baby, M.T.G. Guaratini and P.R.H. Moreno, 2019. In vitro antioxidant and photoprotective activity of five native Brazilian bamboo species. Ind. Crops Prod., 130: 208-215.
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  8. Rambo, D.F., R. Biegelmeyer, N.S. Toson, R.R. Dresch, P.R.H. Moreno and A.T. Henriques, 2019. The genus Erythrina L.: A review on its alkaloids, preclinical and clinical studies. Phytother. Res., 33: 1258-1276.
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  9. Rambo, D.F., R. Biegelmeyer, N.S. Toson, R.R. Dresch, P.R. Moreno and A.T. Henriques, 2019. Box-Behnken experimental design for extraction optimization of alkaloids from Erythrina verna Vell. trunk barks and LC method validation. Ind. Crops Prod., 133: 250-258.
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  10. Murakami, C., R.S.A. Cabral, K.S. Gomes, T.A. Costa-Silva and M. Amaral et al., 2019. Hedyosulide, a novel trypanosomicidal sesterterpene lactone from Hedyosmum brasiliense Mart. ex Miq. Phytochem. Lett., 33: 6-11.
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  11. Oliveira, D.C., T.M. Kaneko, M.C.M. Young, C. Murakami, I. Cordeiro and P.R.H. Moreno, 2018. Chemical composition, antimicrobial and antioxidant activities of Eugenia dysenterica DC essential oil. Emerg. Sci. J., 2: 410-416.
  12. Ferreira, A.K.R., F.R. Lourenco, M.C.M. Young, M.E.L. Lima and I. Cordeiro et al., 2018. Chemical composition and biological activities of Guatteria elliptica RE Fries (Annonaceae) essential oils. J. Essential Oil Res., 30: 69-76.
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  13. Esteves-Pedro, N.M., K. Sugibayashi, E.A. Ostrosky, M. Ferrari and B.D.S. Sufi et al., 2018. Validation cytotoxicity assay for lipophilic substances. Curr. Topics Med. Chem., 18: 275-286.
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  14. Silva, F.L., J.L. da Silva, J.M. Silva, L.S. Marcolin and V.L. Nouailhetas et al., 2017. Antispasmodic activity from Serjania caracasana fractions and their safety. Rev. Bras. Farmacognosia, 27: 346-352.
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  15. Rinaldi, M.V., I.E. Diaz, I.B. Suffredini and P.R. Moreno, 2017. Alkaloids and biological activity of beriba (Annona hypoglauca). Rev. Bras. Farmacogn., 27: 77-83.
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  16. Rajca-Ferreira, A.K., T.M. Kaneko, A. Sartoratto, D.R. de Morais and M.N. Eberlin et al., 2017. Antimicrobial, antioxidant, antitumor activities of Guatteria elliptica RE Fries (Annonaceae) alkaloids and their safety. Int. J. Scient. Eng. Res., 8: 1130-1135.
  17. Murakami, C., I. Cordeiro, M. Scotti, P. Moreno ands M. Young, 2017. Chemical composition, antifungal and antioxidant activities of Hedyosmum brasiliense Mart. ex Miq.(Chloranthaceae) essential oils. Medicines, Vol. 4. 10.3390/medicines4030055.
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  18. Machado, K.N., T.M. Kaneko, M.C.M. Young, C. Murakami, I. Cordeiro and P.R.H. Moreno, 2017. Chemical composition, antimicrobial and antioxidant activities of essential oils from two Avicennia schaueriana Stapf & Leechm. Ex Moldenke (Acanthaceae) populations. Medicines, Vol. 4. 10.3390/medicines4020026.
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  19. Wasicky, A., L.S. Hernandes, A. Vetore-Neto, P.R. Moreno, E.M. Bacchi, E.T.M. Kato and M. Yoshida, 2015. Evaluation of gastroprotective activity of Passiflora alata. Rev. Bras. Farmacogn., 25: 407-412.
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  20. Raggi, L., M.C.M. Young, I. Cordeiro and P.R. Moreno, 2015. Differentiation of two Porophyllum ruderale (Jacq.) Cass. subspecies by the essential oil composition. J. Essential Oil Res., 27: 30-33.
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  21. Nascimento, A.L., L. Raggi, M.C.M. Young and P.R. Moreno, 2015. Chemical characterization of the volatile compounds of the flowers of Bidens segetum Martius ex Colla (Asteraceae). J. Essential Oil Res., 27: 70-75.
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  22. Silva, F.L., P.R. Moreno, R. Braz-Filho, J.F. Tavares and J.M. Barbosa-Filho, 2014. Chemical constituents of Cardiospermum corindum L. and their distribution in Sapindaceae. Biochem. Syst. Ecol., 57: 137-140.
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  23. Lacerda, A.C.L., C.H.R. Serra, A. Martin, P.R.H. Moreno and T.M. Kaneko, 2014. Confocal raman evaluation of stratum corneum biomimetic model membrane for study of the safety and efficacy of permeation enhancers. IFSCC Magaz., 17: 7-10.
  24. Andrade, J.M.M., C.D.S. Passos, R.R. Dresch, M.A. Kieling-Rubio, P.R.H. Moreno and A.T. Henriques, 2014. Chemical analysis, antioxidant, antichemotactic and monoamine oxidase inhibition effects of some pteridophytes from Brazil. Pharmacogn. Magaz., 10: S100-S109.
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  25. Santos, A.P. and P.R.H. Moreno, 2013. Alkaloids Derived from Histidine: Imidazole (Pilocarpine, Pilosine). In: Natural Products: Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenes, Ramawat, K.G. and J.M. Merillon (Eds.). Springer, Berlin, Germany, ISBN: 978-3-642-22143-9, pp: 861-882.
  26. Rambo, D.F., M.V. Vignoli-Silva, R.R. Dresch, C.S. Passos and R. Biegelmeyer et al., 2013. Morphoanatomical study of the bark of Erythrina verna Vell. and determination of physicochemical parameters for quality control of plant-raw material. Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, 12: 243-256.
  27. Oliani, J., C.A.T. Siqueira, A. Sartoratto, C.L. Queiroga and P.R.H. Moreno et al., 2013. Chemical composition and in vitro antiprotozoal activity of the volatile oil from leaves of Annona crassiflora Mart.(Annonaceae). Pharmacologyonline, 3: 8-15.
    Direct Link  |  
  28. Murakami, C., J.H. Lago, F.F. Perazzo, K.S. Ferreira, M.E. Lima, P.R. Moreno and M.C. Young, 2013. Chemical composition and antimicrobial activity of essential oils from Chromolaena laevigata during flowering and fruiting stages. Chem. Biodiversity, 10: 621-627.
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  29. Morgante, P.G., F. Vicente, J.V. Coffani-Nunes and P.R.H. Moreno, 2013. Establishment of simple and efficient methods for plant material harvesting and storage to allow DNA extraction from a myrtaceae species with medicinal potential. Int. J. Genomic Med., Vol. 1. 10.4172/2332-0672.1000109.
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  30. Moreno, H., R. Paulo, F. da Costa-Issa, A.K. Rajca-Ferreira, M.A. Pereira and T.M. Kaneko, 2013. Native Brazilian plants against nosocomial infections: A critical review on their potential and the antimicrobial methodology. Curr. Topics Med. Chem., 13: 3040-3078.
    Direct Link  |  
  31. Cabral, R.S., M.C. Sartori, I. Cordeiro, C.L. Queiroga and M.N. Eberlin et al., 2012. Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus. Rev. Bras. Farmacogn., 22: 374-380.
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  32. iqueira, C.A., J. Oliani, A. Sartoratto, C.L. Queiroga and P.R. Moreno et al., 2011. Chemical constituents of the volatile oil from leaves of Annona coriacea and in vitro antiprotozoal activity. Rev. Bras. Farmacogn., 21: 33-40.
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  33. Lima, M.E.L., I. Cordeiro and P.R.H. Moreno, 2011. [Structure of the tree component in montane tropical rain forest in the Parque Natural Municipal Nascentes de Paranapiacaba (PNMNP), Santo Andre, SÂo Paulo State, Brazil]. Hoehnea, 38: 73-96.
  34. Souza, A.D., E.M.C. Lopes, M.C.D. Silva, I. Cordeiro, M.C.M. Young, M.E. Sobral and P.R. Moreno, 2010. Chemical composition and acetylcholinesterase inhibitory activity of essential oils of Myrceugenia myrcioides (Cambess.) O. Berg and Eugenia riedeliana O. Berg, Myrtaceae. Rev. Bras. Farmacogn., 20: 175-179.
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  35. Linck, V.M., A.L. da Silva, M. Figueiro, E.B. Caramao, P.R.H. Moreno and E. Elisabetsky, 2010. Effects of inhaled Linalool in anxiety, social interaction and aggressive behavior in mice. Phytomedicine, 17: 679-683.
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  36. Ito, R.K., I. Cordeiro, M.E.L. Lima and P.R.H. Moreno, 2010. Chemical composition and antimicrobial activity of the essential oil from Rollinia sericea (RE Fr.) RE Fr.(Annonaceae) leaves. J. Essential Oil Res., 22: 419-421.
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  37. Apel, M.A., M.E. Lima, M. Sobral, M.C.M. Young and I. Cordeiro et al., 2010. Anti-inflammatory activity of essential oil from leaves of Myrciaria tenella and Calycorectes sellowianus. Pharm. Biol., 48: 433-438.
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  38. Andrade, J.M.M., R. Biegelmeyer, C.A. Xavier, S.A. Bordignon and P.R. Moreno et al., 2010. Essential oil constituents of Psychotria leiocarpa. Chem. Nat. Compounds, 46: 649-650.
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  39. Souza, A., M.C. Silva, E.M. Cardoso-Lopes, I. Cordeiro, M.E. Sobral, M.C.M. Young and P.R. Moreno, 2009. Differential acetyl cholinesterase inhibition by volatile oils from two specimens of Marlierea racemosa (Myrtaceae) collected from different areas of the Atlantic rain forest. Nat. Prod. Commun., 4: 1143-1146.
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  40. Moreno, P.R.H., M.E.L. Lima, M.B.R. Caruzo, D.S.C. Torres, I. Cordeiro and M.C.M. Young, 2009. Chemical composition and antimicrobial activity of the essential oil from Croton heterocalyx Baill.(Euphorbiaceae s.s.) leaves. J. Essential Oil Res., 21: 190-192.
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  41. Linck, V.D.M., A.L. da Silva, M. Figueiro, A.L. Piato and A.P. Herrmann et al., 2009. Inhaled linalool-induced sedation in mice. Phytomedicine, 16: 303-307.
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  42. Ladeira, A.M., G.B. da Silva, L. Raggi, M.C.M. Young, D.G. Agripino, M.E. Lima and P.R. Moreno, 2009. Chemical composition and antimicrobial activities of the essential oil of Hypericum cordatum (Vell. Conc.) N. Robson (Hypericaceae). J. Essential Oil Res., 21: 558-560.
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  43. De Assis, C.M., P.R. Moreno, M.C.M. Young, I.P.D.A. Campos and I.B. Suffredini, 2009. [Isolation and evaluation of the biological activity related to the major alkaloids in Tabernaemontana angulata Mart. ex Mull. Arg., Apocynaceae]. Braz. J. Pharmacogn., 19: 626-631.
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  44. Apel, M.A., M.E. Lima, P.R.H. Moreno, M.C.M. Young, I. Cordeiro and A.T. Henriques, 2009. Constituents of leaves essential oil of Talauma ovata A. St.-Hil.(Magnoliaceae). J. Essential Oil Res., 21: 52-53.
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  45. Vallilo, M.I., P.R.H. Moreno, E. de Oliveira, L.C.A. Lamardo and M.L. Garbelotti, 2008. [Chemical composition of Campomanesia xanthocarpa Berg-Myrtaceae fruit]. Cienc. Tecnol. Aliment., 28: 231-237.
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  46. Limberger, R.P., A.T. Henriques, M.A. Apel, M.E.L. Lima, P.R. Moreno and I. Cordeiro, 2008. Essential oil from leaves and stem bark of southeastern Drimys brasiliensis Miers (Winteraceae). J. Essential Oil Res., 20: 504-506.
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  47. Silva, L.D., G.H. Oniki, D.G. Agripino, P.R. Moreno, M.C.M. Young, M.A.S. Mayworm and A.M. Ladeira, 2007. [Bicyclogermacrene, resveratrol and fungitoxic activity on leaves extracts of Cissus verticillata L. Nicolson & Jarvis (Vitaceae)]. Rev. Bras. Farmacogn., 17: 361-367.
  48. Sartorelli, P., A.D. Marquioreto, A. Amaral-Baroli, M.E.L. Lima and P.R.H. Moreno, 2007. Chemical composition and antimicrobial activity of the essential oils from two species of Eucalyptus. Phytother. Res., 21: 231-233.
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  49. Moreno, P.R.H., M.E.L. Lima, M. Sobral, M.C.M. Young and I. Cordeiro et al., 2007. Essential oil composition of fruit colour varieties of Eugenia brasiliensis Lam. Sci. Agricola, 64: 428-432.
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  50. Vallilo, M.I., L.C.A. Lamardo, M.L. Gaberlotti, E.D. Oliveira and P.R.H. Moreno, 2006. [Chemical composition of Campomanesia adamantium (Cambessedes) O. Berg’ fruits]. Cienc. Tecnol. Aliment., 26: 725-955.
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  51. Lima, M.E.L., I. Cordeiro, M.C.M. Young, M.E. Sobra and P.R.H. Moreno, 2006. Antimicrobial activity of the essential oil from two specimens of Pimenta pseudocaryophyllus (Gomes) LR Landrum (Myrtaceae) native from Sao Paulo State-Brazil. Pharmacologyonline, 3: 589-593.
  52. De Assis, J.R., I.B. Suffredini, P.R.H. Moreno, M.C. Young, A.D. Varella, R.N. Younes and M.M. Bernardi, 2006. Analysis of the toxic potential of Palicourea corymbifera (MÊll. Arg.) Standl. in laboratory animals. Res. Vet. Sci., 80: 209-217.
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  53. Apel, M.A., M.E.L. Lima, A. Souza, I. Cordeiro and M.C.M. Young et al., 2006. Screening of the biological activity from essential oils of native species from the Atlantic rain forest (SÂo Paulo-Brazil). Pharmacologyonline, 3: 376-383.
  54. Lago, J.H.G., M.L. Cornelio, P.R.H. Moreno, M.A. Apel and R.P. Limberger et al., 2005. Sesquiterpenes from essential oil from fruits of Guarea macrophylla Vahl ssp. tuberculata (Meliaceae). J. Essent. Oil Res., 17: 84-85.
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  55. Fischer, D.C., R.P. Limberger, A.T. Henriques and P.R. Moreno, 2005. Essential oils from leaves of two Eugenia brasiliensis specimens from southeastern Brazil. J. Essential Oil Res., 17: 499-500.
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  56. Fischer, D.C., R.P. Limberger, A.T. Henriques and P.R. Moreno, 2005. Essential oils from fruits and leaves of Siparuna guianensis (Aubl.) Tulasne from southeastern Brazil. J. Essential Oil Res., 17: 101-102.
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  57. Cornelio, M.L., J.H.G. Lago, P.R.H. Moreno, M.A. Apel and A.T. Henriques, 2005. Volatile oil composition of Aspidosperma cylindrocarpon Muell. Arg. leaves. J. Essent. Oil Res., 17: 310-311.
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  58. Santos, A.P., M.C. Lopes, R.P. Limberger, M.A. Apel, A.T. Henriques and P.R.H. Moreno, 2004. Analysis of the volatile oil from Pilocarpus pennatifolius Lemmaire (Rutaceae) leaves by GC-MS. Flavour Fragr. J., 19: 325-326.
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  59. Santos, A.P. and P.R.H. Moreno, 2004. Pilocarpus spp.: A survey of its chemical constituents and biological activities. Rev. Bras. Cien. Farmaceut., 40: 116-137.
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  60. Lopes, S., G.L. von Poser, V.A. Kerber, F.M. Farias and E.L. Konrath et al., 2004. Taxonomic significance of alkaloids and iridoid glucosides in the tribe Psychotrieae (Rubiaceae). Biochem. Syst. Ecol., 32: 1187-1195.
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  61. Lago, J.H.G., P. de Avila Jr., E.M. de Aquino, P.R.H. Moreno and M.T. Ohara et al., 2004. Volatile oils from leaves and stem barks of Cedrela fissilis (Meliaceae): Chemical composition and antibacterial activities. Flavour Fragr. J., 19: 448-451.
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  62. Fischer, D.C.H., N.C. de Amorim Gualda, D. Bachiega, C.S. Carvalho and F.N. Lupo et al., 2004. In vitro screening for antiplasmodial activity of isoquinoline alkaloids from Brazilian plant species. Acta Trop., 92: 261-266.
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  63. Cornelio, M.L., J.H.G. Lago, P.R.H. Moreno, A.T. Henriques and R.P. Limberger, 2004. Essential oil from Aspidosperma polyneuron Muell. Arg. leaves. J. Essent. Oil Res., 16: 246-247.
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  64. Agripino, D.G., M.E.L. Lima, M.R. da Silva, C.I. Meda and V.D.S. Bolzani et al., 2004. Screening of Brazilian plants for antimicrobial and dnadamaging activities: I. Atlantic rain forest-ecological station Jureia-Itatins. Biota Neotrop., Vol. 4, No. 2. 10.1590/S1676-06032004000200009.
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  65. Lago, J.H.G., P. de Avila, P.R.H. Moreno, R.P. Limberger, M.A. Apel and A.T. Henriques, 2003. Analysis, comparison and variation on the chemical composition from the leaf volatile oil of Xylopia aromatica (Annonaceae). Biochem. Syst. Ecol., 6: 669-672.
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  66. Lago, J.H.G., I.C. Moreira, T.M. Tanizaki, P.R.H. Moreno and N.F. Roque et al., 2003. Mono and sesquiterpenes from the leaf essential oil of Xylopia brasiliensis Spreng. (Annonaceae). J. Essent. Oil Res., 15: 406-407.
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  67. Ten Hoopen, H.J.G., J.L. Vinke, P.R.H. Moreno, R. Verpoorte and J.J. Heijnen, 2002. Influence of temperature on growth and ajmalicine production by Catharantus roseus suspension cultures. Enzyme Microb. Technol., 30: 56-65.
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  68. Nunez, C.V., J.H.G. Lago, M.C. Amendola, P.R.H. Moreno, A. Peltenburg-Looman and N.F. Roque, 2002. Analysis of essential oil from stems and leaves of Mikania sp. nov. (Asteraceae). J. Essent. Oil Res., 14: 425-426.
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  69. Sartorelli, P., P.J. Benevides, R.M. Ellensohn, M.V. Rocha, P.R. Moreno and M.J. Kato, 2001. Enantioselective conversion of p-hydroxypropenylbenzene to (+)-conocarpan in Piper regnellii. Plant Sci., 161: 1083-1088.
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  70. Limberger, R.P., P.R.H. Moreno, F.M. Farias, M. Sobral and A.T. Henriques, 2001. Essential oil of Myrrhinium atropurpureum Schott (Myrtaceae) leaves. J. Essent. Oil Res., 13: 47-48.
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  71. Limberger, R.P., M.E.G. Sobral, J.A.S. Zuanazzi, P.R.H. Moreno, E.E.S. Schapoval and A.T. Henriques, 2001. Biological activities and essential oil composition of leaves of Blepharocalyx salicifolius. Pharmaceut. Biol., 39: 308-311.
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  72. Limberger, R.P., M.A. Apel, M. Sobral, P.R.H. Moreno, A.T. Henriques and C. Menut, 2001. Chemical composition of essential oils from some Campomanesia species (Myrtaceae). J. Essent. Oil Res., 13: 113-115.
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  73. Limberger, R.P., A.L. Aboy, V.L. Bassani, P.R.H. Moreno, M.R. Ritter and A.T. Henriques, 2001. Essential oils from four Mikania species (Asteraceae). J. Essent. Oil Res., 13: 225-228.
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  74. Apel, M.A., R.P. Limberger, M. Sobral, C. Menut and A.T. Henriques, 2001. Chemical composition of the essential oil of Neomitranthes cordifolia (D. Legr.) D. Legr. J. Essent. Oil Res., 13: 250-251.
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  75. Alvarenga, S.A.V., J.P. Gastmans, G. do Vale Rodrigues, P.R.H. Moreno and V. de Paulo Emerenciano, 2001. A computer-assisted approach for chemotaxonomic studies-diterpenes in Lamiaceae. Phytochemistry, 56: 583-595.
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  76. Lopes, S.O., P.R.H. Moreno and A.T. Henriques, 2000. Growth characteristics and chemical analysis of Psychotria carthagenensis cell suspension cultures. Enzyme Microb. Technol., 26: 259-264.
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  77. Van Tegelen, L.J.P., P.R.H. Moreno, A.F. Croes, R. Verpoorte and G.J. Wullems, 1999. Purification and cDNA cloning of isochorismate synthase from elicited cell cultures of Catharanthus roseus. Plant Physiol., 119: 705-712.
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  78. Collu, G., H.H. Bink, P.R.H. Moreno, R. van der Heijden and R. Verpoorte, 1999. Determination of the activity of the cytochrome p450 enzyme geraniol 10-hydroxylase in plants by high-performance liquid chromatography. Phytochem. Anal., 10: 314-318.
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  79. Verpoorte, R., R. van der Heijden and P.R.H. Moreno, 1997. Biosynthesis of Terpenoid Indole Alkaloids in Catharanthus roseus Cells. In: The Alkaloids: Chemistry and Pharmacology, Cordell, G.A. (Ed.). Vol. 49, Chapter 3, Academic Press, San Diego, USA., ISBN: 978-0-12-469549-8, pp: 221-299.
  80. Schlatmann, J.E., P.R.H. Moreno, J.L. Vinke, H.J.G. ten Hoopen, R. Verpoorte and J.J. Heijnen, 1997. Gaseous metabolites and the ajmalicine production rate in high density cell cultures of Catharanthus roseus. Enzyme Microb. Technol., 20: 107-115.
    CrossRef  |  Direct Link  |  
  81. Moreno, P.R.H., C. Poulsen, R. van der Heijden and R. Verpoorte, 1996. Effects of elicitation on different metabolic pathways in Catharanthus roseus (L.)G.Don cell suspension cultures. Enzyme Microb. Technol., 18: 99-107.
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  82. Henriques, A.T., A.A. Melo, P.R.H. Moreno, L.L. Ene, J.A.P. Henriques and E.E.S. Schapoval, 1996. Ervatamia coronaria: Chemical constituents and some pharmacological activities. J. Ethnopharmacol., 50: 19-25.
    CrossRef  |  PubMed  |  Direct Link  |  
  83. Schlatmann, J.E., P.R.H. Moreno, M. Selles, J.L. Vinke, H.J.G. ten Hoopen, R. Verpoorte and J.J. Heijnen, 1995. Two-stage batch process for the production of ajmalicine by Catharanthus roseus: The link between growth and production stage. Biotechnol. Bioeng., 47: 53-59.
    CrossRef  |  Direct Link  |  
  84. Moreno, P.R.H., R. van der Heijden and R. Verpoorte, 1995. Cell and tissue cultures of Catharanthus roseus: A literature survey. II. Updating from 1988 to 1993. Plant Cell Tissue Org. Cult., 42: 1-25.
    CrossRef  |  Direct Link  |  
  85. Ten Hoopen, H.J.G., W.M. van Gulik, J.E. Schlatmann, P.R.H. Moreno, J.L. Vinke, J.J. Heijnen and R. Verpoorte, 1994. Ajmalicine production by cell cultures of Catharanthus roseus: From shake flask to bioreactor. Plant Cell Tissue Org. Cult., 38: 85-91.
    CrossRef  |  Direct Link  |  
  86. Schlatmann, J.E., P.R.H. Moreno, J.L. Vinke, H.J.G. ten Hoopen, R. Verpoorte and J.J. Heijnen, 1994. Effects of oxygen and nutrients limitation on ajmalicine production and related enzyme activities in high density cultures of Catharanthus roseus. Biotechnol. Bioeng., 44: 461-468.
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  87. Moreno, P.R.H., R. van der Heijden and R. Verpoorte, 1994. Induction of the secondary metabolism in Catharanthus roseus cell suspension cultures in response to UV irradiation and the addition of a benzoic acid derivative. Heterocycles, 2: 457-465.
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  88. Moreno, P.R.H., R. van der Heijden and R. Verpoorte, 1994. Elicitor-mediated induction of isochorismate synthase and accumulation of 2,3-dihydroxy benzoic acid in Catharanthus roseus cell suspension and shoot cultures. Plant Cell Rep., 14: 188-191.
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  89. Moreno, P.R.H., R. van der Heijden and R. Verpoorte, 1993. Effect of terpenoid precursor feeding and elicitation on formation of indole alkaloids in cell suspension cultures of Catharanthus roseus. Plant Cell Rep., 12: 702-705.
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  90. Moreno, P.R.H., G.L. von Poser, S.M.K. Rates, M. Yoshida, O.R. Gottlieb, I.A. Souza and A.T. Henriques, 1993. Chemical constituents and antitumour acitivity of Nectandra grandiflora. Int. J. Pharmacogn., 31: 189-192.
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  91. Moreno, P.R., J.E. Schlatmann, R. van der Heijden, W.M. van Gulik, H.J. ten Hoopen, R. Verpoorte and J.J. Heijnen, 1993. Induction of ajmalicine formation and related enzyme activities in Catharanthus roseus cells: Effect of inoculum density. Applied Microbiol. Biotechnol., 39: 42-47.
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  92. Moreno, P.R.H., V.M.F. Vargas, H.H.R. Andrade, A.T. Henriques and J.A.P. Henriques, 1991. Genotoxicity of the boldine aporphine alkaloid in prokaryotic and eukaryotic organisms. Mutat. Res./Genet. Toxicol., 260: 145-152.
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